Enzymatic Synthesis of Ricinoleyl Hydroxamic Acid Based on Commercial Castor Oil, Cytotoxicity Properties and Application as a New Anticancer Agent

BACKGROUND: New anticancer agents that rely on natural/healthy, not synthetic/toxic, components are very much needed. METHODS: Ricinoleyl hydroxamic acid (RHA) was synthesized from castor oil and hydroxylamine using Lipozyme TL IM as a catalyst. To optimize the conversion, the effects of the followi...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Nanomedicine
Hauptverfasser: Jahangirian, Hossein, Saleh, Bahram, Kalantari, Katayoon, Rafiee-Moghaddam, Roshanak, Nikpey, Bahareh, Jahangirian, Siavash, Webster, Thomas J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196198/
https://ncbi.nlm.nih.gov/pubmed/32425525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S223796
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