Melatonin Attenuates Calcium Deposition from Vascular Smooth Muscle Cells by Activating Mitochondrial Fusion and Mitophagy via an AMPK/OPA1 Signaling Pathway

Mitochondrial fusion/mitophagy plays a role in cardiovascular calcification. Melatonin has been shown to protect against cardiovascular disease. This study sought to explore whether melatonin attenuates vascular calcification by regulating mitochondrial fusion/mitophagy via the AMP-activated protein...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Chen, Wei Ren, Zhou, Yu Jie, Yang, Jia Qi, Liu, Fang, Wu, Xue Ping, Sha, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196154/
https://ncbi.nlm.nih.gov/pubmed/32377301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5298483
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