JNK Signaling Pathway Suppresses LPS-Mediated Apoptosis of HK-2 Cells by Upregulating NGAL

OBJECTIVE: To explore the role of the c-Jun N-terminal kinase (JNK) signaling pathway in upregulated NGAL expression and its antiapoptotic mechanism in lipopolysaccharide (LPS)-mediated renal tubular epithelial cell injury. METHODS: In vitro, HK-2 cells were divided into five groups (Con, LPS 1 h, L...

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Veröffentlicht in:Int J Inflam
Hauptverfasser: Han, Mei, Pan, Yuxia, Gao, Mengying, Zhang, Junli, Wang, Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196152/
https://ncbi.nlm.nih.gov/pubmed/32373311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/3980507
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