Dynamics of within-host Mycobacterium tuberculosis diversity and heteroresistance during treatment

BACKGROUND: Studying within-host genetic diversity of Mycobacterium tuberculosis (Mtb) in patients during treatment may identify adaptations to antibiotic and immune pressure. Understanding the significance of genetic heteroresistance, and more specifically heterozygous resistance-associated variant...

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Publicado en:EBioMedicine
Autores principales: Nimmo, Camus, Brien, Kayleen, Millard, James, Grant, Alison D., Padayatchi, Nesri, Pym, Alexander S., O'Donnell, Max, Goldstein, Richard, Breuer, Judith, Balloux, François
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2020
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Research paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195533/
https://ncbi.nlm.nih.gov/pubmed/32361247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102747
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