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Implications of variability in cell membrane permeability for design of methods to remove glycerol from frozen-thawed erythrocytes

In North America, red blood cells (RBCs) are currently cryopreserved in a solution of 40% glycerol. While glycerol is not inherently toxic to humans, it must be removed prior to transfusion to prevent intravascular osmotic hemolysis. The current deglycerolization procedure requires about 45 minutes...

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Dettagli Bibliografici
Pubblicato in:Cryobiology
Autori principali: Lahmann, John M., Sanchez, Cynthia Cruz, Benson, James D., Acker, Jason P., Higgins, Adam Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195249/
https://ncbi.nlm.nih.gov/pubmed/31935377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cryobiol.2020.01.006
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