TGF-beta and TNF-alpha cooperatively induce mesenchymal transition of lymphatic endothelial cells via activation of Activin signals

Lymphatic systems play important roles in the maintenance of fluid homeostasis and undergo anatomical and physiological changes during inflammation and aging. While lymphatic endothelial cells (LECs) undergo mesenchymal transition in response to transforming growth factor-β (TGF-β), the molecular me...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yoshimatsu, Yasuhiro, Kimuro, Shiori, Pauty, Joris, Takagaki, Kazuki, Nomiyama, Sanae, Inagawa, Akihiko, Maeda, Kentaro, Podyma-Inoue, Katarzyna A., Kajiya, Kentaro, Matsunaga, Yukiko T., Watabe, Tetsuro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194440/
https://ncbi.nlm.nih.gov/pubmed/32357159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0232356
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