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Validation of a commercial antibody to detect endogenous human nicastrin by immunoblot
Nicastrin (NCSTN) is a transmembrane glycoprotein that is part of the gamma-secretase complex. Gamma-secretase is a protease complex that cleaves type-I single-pass transmembrane proteins. There are many potential substrates for this complex, including NOTCH receptors and amyloid precursor proteins...
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Publicado no: | F1000Res |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
F1000 Research Limited
2020
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7194342/ https://ncbi.nlm.nih.gov/pubmed/32399180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.19803.2 |
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