Rational design of peptides for identification of linear epitopes and generation of neutralizing monoclonal antibodies against DKK2 for cancer therapy

Dickkopf-related protein 2 (DKK2)is a member of the Dickkopf family in Wnt signaling pathway. Recently, we found that antibodies against DKK2 could activate natural killer (NK) and CD8+ T cells in tumors and inhibit tumor growth. In this paper, we report the rational design of peptides for identific...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Antib Ther
मुख्य लेखकों: Zhao, Rongqing, Xiao, Qian, Li, Maohua, Ren, Wenlin, Xia, Chenxi, Liu, Xudong, Li, Yingzi, Tan, Tan, Wu, Dianqing, Sun, Le
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2020
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194219/
https://ncbi.nlm.nih.gov/pubmed/32391516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tbaa004
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