Osthole, a Natural Plant Derivative Inhibits MRGPRX2 Induced Mast Cell Responses

Mast cells are tissue-resident innate immune cells known for their prominent role in mediating allergic reactions. MAS-related G-protein coupled receptor-X2 (MRGPRX2) is a promiscuous G-protein coupled receptor (GPCR) expressed on mast cells that is activated by several ligands that share cationic a...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Callahan, Brianna N., Kammala, Ananth K., Syed, Meesum, Yang, Canchai, Occhiuto, Christopher J., Nellutla, Rithvik, Chumanevich, Alena P., Oskeritzian, Carole A., Das, Rupali, Subramanian, Hariharan
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194083/
https://ncbi.nlm.nih.gov/pubmed/32391014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00703
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