GTS-21, an α7nAChR agonist, suppressed the production of key inflammatory mediators by PBMCs that are elevated in COPD patients and associated with impaired lung function

Chronic obstructive pulmonary disease (COPD) is a lung inflammatory disease characterized by progressive airflow limitation, chronic respiratory symptoms and frequent exacerbations. There is an unmet need to identify novel therapeutic alternatives beside bronchodilators that prevent disease progress...

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Bibliographic Details
Published in:Immunobiology
Main Authors: Douaoui, Sana, Djidjik, Reda, Boubakeur, Mokhtar, Ghernaout, Merzak, Touil-boukoffa, Chafia, Oumouna, Mustapha, Derrar, Fawzi, Amrani, Yassine
Format: Artigo
Language:Inglês
Published: Elsevier GmbH. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194070/
https://ncbi.nlm.nih.gov/pubmed/32387130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2020.151950
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