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Inactivation of FAM20B causes cell fate changes in annulus fibrosus of mouse intervertebral disc and disc defects via the alterations of TGF-β and MAPK signaling pathways

Intervertebral disc (IVD) disorder is often caused by the defect of annulus fibrosus (AF), especially that of the outer AF. Studies about the mechanisms governing the development of the outer AF are needed for a better understanding of pathogenesis of IVD defects. Glycosaminoglycans (GAGs) are essen...

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Dettagli Bibliografici
Pubblicato in:Biochim Biophys Acta Mol Basis Dis
Autori principali: Saiyin, Wuliji, Li, Lili, Zhang, Hua, Lu, Yongbo, Qin, Chunlin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7194007/
https://ncbi.nlm.nih.gov/pubmed/31513834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.165555
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