Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole

BACKGROUND AND PURPOSE: Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adv...

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Pubblicato in:Front Pharmacol
Autori principali: Udawatte, Nadeeka S., Kang, Sung Wook, Wang, Yue, Arumugam, Thiruma V., Seneviratne, Chaminda J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193989/
https://ncbi.nlm.nih.gov/pubmed/32390849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00511
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