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A novel GPER antagonist protects against the formation of estrogen-induced cholesterol gallstones in female mice

Many clinical studies and epidemiological investigations have clearly demonstrated that women are twice as likely to develop cholesterol gallstones as men, and oral contraceptives and other estrogen therapies dramatically increase that risk. Further, animal studies have revealed that estrogen promot...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Main Authors: DeLeon, Chelsea, Wang, Helen H., Gunn, Joseph, Wilhelm, McKenna, Cole, Aidan, Arnett, Stacy, Wang, David Q-H., Arnatt, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193967/
https://ncbi.nlm.nih.gov/pubmed/32127396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000592
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