Oxysterol 25-hydroxycholesterol as a metabolic pathophysiological factors of osteoarthritis induces apoptosis in primary rat chondrocytes

The aim of the present study was to investigate the pathophysiological etiology of osteoarthritis that is mediated by the apoptosis of chondrocytes exposed to 25-hydroxycholesterol (25-HC), an oxysterol synthesized by the expression of cholesterol-25-hydroxylase (CH25H) under inflammatory conditions...

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Detalhes bibliográficos
Publicado no:Korean J Physiol Pharmacol
Main Authors: Seo, Yo-Seob, Cho, In-A, Kim, Tae-Hyeon, You, Jae-Seek, Oh, Ji-Su, Lee, Gyeong-Je, Kim, Do Kyung, Kim, Jae-Sung
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193916/
https://ncbi.nlm.nih.gov/pubmed/32392916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2020.24.3.249
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