NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.

NMDA receptor (NMDAR) antagonists such as ketamine, can reproduce many of the symptoms of schizophrenia. A reliable indicator of NMDAR channel blocker action in vivo is the augmentation of neuronal oscillation power. Since the coordinated and rhythmic activation of neuronal assemblies (oscillations)...

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Udgivet i:Brain Res
Main Authors: Mao, Zhihao, He, Shengxi, Mesnard, Christopher, Synowicki, Paul, Zhang, Yuning, Chung, Lucy, Wiesman, Alex I., Wilson, Tony W., Monaghan, Daniel T.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193694/
https://ncbi.nlm.nih.gov/pubmed/31786200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2019.146571
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