Sensitive detection methods are key to identify secondary EGFR c.2369C>T p.(Thr790Met) in non-small cell lung cancer tissue samples

BACKGROUND: Correct identification of the EGFR c.2369C>T p.(Thr790Met) variant is key to decide on a targeted therapeutic strategy for patients with acquired EGFR TKI resistance in non-small cell lung cancer. The aim of this study was to evaluate the correct detection of this variant in 12 tumor...

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Publicado no:BMC Cancer
Main Authors: Keppens, Cleo, Dequeker, Elisabeth M. C., Rouleau, Etienne, ’t Hart, Nils, Bubendorf, Lukas, Dufraing, Kelly, Garrec, Céline, Guéguen, Paul, Lamy, Aude, Marchetti, Antonio, Pauwels, Patrick, Ryska, Ales, Tack, Véronique, Tornillo, Luigi, Van Casteren, Kaat, von der Thüsen, Jan H., Zwaenepoel, Karen, Lissenberg-Witte, Birgit, Thunnissen, Erik, Schuuring, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193365/
https://ncbi.nlm.nih.gov/pubmed/32357863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06831-3
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