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Safety, tolerability, and response rates of daratumumab in relapsed AL amyloidosis: results of a phase 2 study

Daratumumab, a monoclonal CD38 antibody, is approved in the treatment of myeloma, but its efficacy and safety in light-chain (AL) amyloidosis has not been formally studied. This prospective phase 2 trial of daratumumab monotherapy for the treatment of AL amyloidosis was designed to determine the saf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Sanchorawala, Vaishali, Sarosiek, Shayna, Schulman, Amanda, Mistark, Meredith, Migre, Mary Ellen, Cruz, Ramon, Sloan, J. Mark, Brauneis, Dina, Shelton, Anthony C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193185/
https://ncbi.nlm.nih.gov/pubmed/31978210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004436
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