Quantifying the Predictive Accuracy of a Polygenic Risk Score for Predicting Incident Cancer Cases : Application to the CARTaGENE Cohort

With the increasing use of polygenic risk scores (PRS) there is a need for adapted methods to evaluate the predictivity of these tools. In this work, we propose a new pseudo-R(2) criterion to evaluate PRS predictive accuracy for time-to-event data. This new criterion is related to the score statisti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Genet
Principais autores: Duhazé, Julianne, Jantzen, Rodolphe, Payette, Yves, De Malliard, Thibault, Labbé, Catherine, Noisel, Nolwenn, Broët, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193029/
https://ncbi.nlm.nih.gov/pubmed/32391062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00408
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados