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Alpha-lipoic acid inhibits proliferation and migration of human vascular endothelial cells through downregulating HSPA12B/VEGF signaling axis

Endothelial cells play essential roles in angiogenesis. Heat shock protein A12B (HSPA12B), a novel member of the multigene Hsp70 family, expresses specifically in endothelial cells. Alpha-lipoic acid (LA) has been used for the treatment of human diabetic complications for more than 20 years. However...

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Dettagli Bibliografici
Pubblicato in:Cell Stress Chaperones
Autori principali: Ni, Yan, Wang, Juan, Wang, Zhuyao, Zhang, Xiaojin, Cao, Xiaofei, Ding, Zhengnian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192994/
https://ncbi.nlm.nih.gov/pubmed/32219685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-020-01086-0
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