The therapeutic effectiveness of (177)Lu-lilotomab in B-cell non-Hodgkin lymphoma involves modulation of G2/M cell cycle arrest

Some patients with B-cell non-Hodkin lymphoma Lymphoma (NHL) become refractory to rituximab (anti-CD20 antibody) therapy associated with chemotherapy. Here, the effect of the anti-CD37 antibody-radionuclide conjugate lutetium-177 ((177)Lu)-lilotomab (Betalutin(®)) was investigated in preclinical mod...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Pichard, Alexandre, Marcatili, Sara, Karam, Jihad, Constanzo, Julie, Ladjohounlou, Riad, Courteau, Alan, Jarlier, Marta, Bonnefoy, Nathalie, Patzke, Sebastian, Stenberg, Vilde, Coopman, Peter, Cartron, Guillaume, Navarro-Teulon, Isabelle, Repetto-Llamazares, Ada, Heyerdahl, Helen, Dahle, Jostein, Bardiès, Manuel, Pouget, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192854/
https://ncbi.nlm.nih.gov/pubmed/31836849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0677-4
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