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A newly identified Leishmania IF4E-interacting protein, Leish4E-IP2, modulates the activity of cap-binding protein paralogs

Translation of most cellular mRNAs in eukaryotes proceeds through a cap-dependent pathway, whereby the cap-binding complex, eIF4F, anchors the preinitiation complex at the 5′ end of mRNAs and regulates translation initiation. The requirement of Leishmania to survive in changing environments can expl...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Tupperwar, Nitin, Meleppattu, Shimi, Shrivastava, Rohit, Baron, Nofar, Gilad, Ayelet, Wagner, Gerhard, Léger-Abraham, Mélissa, Shapira, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192595/
https://ncbi.nlm.nih.gov/pubmed/32232353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa173
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