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Direct observation and analysis of TET-mediated oxidation processes in a DNA origami nanochip
DNA methylation and demethylation play a key role in the epigenetic regulation of gene expression; however, a series of oxidation reactions of 5-methyl cytosine (5mC) mediated by ten-eleven translocation (TET) enzymes driving demethylation process are yet to be uncovered. To elucidate the relationsh...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7192588/ https://ncbi.nlm.nih.gov/pubmed/32170318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa137 |
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