Collective forces of tumor spheroids in three-dimensional biopolymer networks

We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is computationally complex due to the variable cell sh...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mark, Christoph, Grundy, Thomas J, Strissel, Pamela L, Böhringer, David, Grummel, Nadine, Gerum, Richard, Steinwachs, Julian, Hack, Carolin C, Beckmann, Matthias W, Eckstein, Markus, Strick, Reiner, O'Neill, Geraldine M, Fabry, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192581/
https://ncbi.nlm.nih.gov/pubmed/32352379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51912
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