Complement Fragments are Biomarkers of Antibody-Mediated Endothelial Injury

Antibody-mediated rejection (AbMR) adversely affects long-term graft survival in kidney transplantation. Currently, the diagnosis of AbMR requires a kidney biopsy, and detection of complement C4d deposition in the allograft is one of the diagnostic criteria. Complement activation also generates seve...

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Bibliographic Details
Published in:Mol Immunol
Main Authors: Stites, Erik, Renner, Brandon, Laskowski, Jennifer, Quintrec, Moglie Le, You, Zhiying, Freed, Brian, Cooper, James, Jalal, Diana, Thurman, Joshua M.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192552/
https://ncbi.nlm.nih.gov/pubmed/31884386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2019.12.011
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