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Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies

Genome-wide association studies (GWASs) have identified many SNPs associated with various common diseases. Understanding the biological functions of these identified SNP associations requires identifying disease/trait relevant tissues or cell types. Here, we develop a network method, CoCoNet, to fac...

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Vydáno v:PLoS Genet
Hlavní autoři: Shang, Lulu, Smith, Jennifer A., Zhou, Xiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192514/
https://ncbi.nlm.nih.gov/pubmed/32310941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008734
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