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Flux-based hierarchical organization of Escherichia coli’s metabolic network

Biological networks across scales exhibit hierarchical organization that may constrain network function. Yet, understanding how these hierarchies arise due to the operational constraint of the networks and whether they impose limits to molecular phenotypes remains elusive. Here we show that metaboli...

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Pubblicato in:PLoS Comput Biol
Autori principali: Robaina-Estévez, Semidán, Nikoloski, Zoran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192501/
https://ncbi.nlm.nih.gov/pubmed/32310959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007832
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