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Chemistry and Neurotrophic Activities of (–)-Talaumidin and Its Derivatives

(–)-Talaumidin (1), a 2,5-biaryl-3,4-dimethyltetrahydrofuran lignan isolated from Aristolochia arcuata Masters, exhibits significant neurite-outgrowth promotion and neuroprotection in primary cultured rat cortical neurons and in NGF-differentiated PC12 cells. The first enantioselective total synthes...

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Detalhes bibliográficos
Publicado no:Front Chem
Main Authors: Harada, Kenichi, Kubo, Miwa, Fukuyama, Yoshiyasu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192021/
https://ncbi.nlm.nih.gov/pubmed/32391327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00301
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