A clioquinol-containing Pluronic(®) F127 polymeric micelle system is effective in the treatment of visceral leishmaniasis in a murine model

A clioquinol (ICHQ)-containing Pluronic(®) F127 polymeric micelle system (ICHQ/Mic) was recently shown to be effective against Leishmania amazonensis infection in a murine model. In the present study, ICHQ/Mic was tested against L. infantum infection. BALB/c mice (n = 12 per group) were infected wit...

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Publicado en:Parasite
Main Authors: Tavares, Grasiele S.V., Mendonça, Débora V.C., Pereira, Isabela A.G., Oliveira-da-Silva, João A., Ramos, Fernanda F., Lage, Daniela P., Machado, Amanda S., Carvalho, Lívia M., Reis, Thiago A.R., Perin, Luísa, Carvalho, Ana Maria R.S., Ottoni, Flaviano M., Ludolf, Fernanda, Freitas, Camila S., Bandeira, Raquel S., Silva, Alessandra M., Chávez-Fumagalli, Miguel A., Duarte, Mariana C., Menezes-Souza, Daniel, Alves, Ricardo J., Roatt, Bruno M., Coelho, Eduardo A.F.
Formato: Artigo
Idioma:Inglês
Publicado: EDP Sciences 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191975/
https://ncbi.nlm.nih.gov/pubmed/32351209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/parasite/2020027
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