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Sitagliptin Inhibits Extracellular Matrix Accumulation and Proliferation in Lung Fibroblasts
BACKGROUND: Fibroblasts activation-induced fibrosis can cause idiopathic pulmonary fibrosis (IPF). Excessive activation of fibroblasts contributes to poor healing or severe visceral fibrosis and even organ dysfunction. Sitagliptin acts as a dipeptidyl peptidase 4 inhibitor to reduce glucose level in...
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| Veröffentlicht in: | Med Sci Monit |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Scientific Literature, Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7191949/ https://ncbi.nlm.nih.gov/pubmed/32301442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.922644 |
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