Renoprotective and Immunomodulatory Effects of GDF15 following AKI Invoked by Ischemia-Reperfusion Injury

BACKGROUND: Gdf15 encodes a TGF-β superfamily member that is rapidly activated in response to stress in multiple organ systems, including the kidney. However, there has been a lack of information about Gdf15 activity and effects in normal kidney and in AKI. METHODS: We used genome editing to generat...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Liu, Jing, Kumar, Sanjeev, Heinzel, Andreas, Gao, Michael, Guo, Jinjin, Alvarado, Gregory F., Reindl-Schwaighofer, Roman, Krautzberger, A. Michaela, Cippà, Pietro E., McMahon, Jill, Oberbauer, Rainer, McMahon, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191932/
https://ncbi.nlm.nih.gov/pubmed/32034106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019090876
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