Low abundance of NDUFV2 and NDUFS4 subunits of the hydrophilic complex I domain and VDAC1 predicts mammalian longevity

Mitochondrial reactive oxygen species (ROS) production, specifically at complex I (Cx I), has been widely suggested to be one of the determinants of species longevity. The present study follows a comparative approach to analyse complex I in heart tissue from 8 mammalian species with a longevity rang...

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Publicat a:Redox Biol
Autors principals: Mota-Martorell, Natalia, Jove, Mariona, Pradas, Irene, Sanchez, Isabel, Gómez, José, Naudi, Alba, Barja, Gustavo, Pamplona, Reinald
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191849/
https://ncbi.nlm.nih.gov/pubmed/32353747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101539
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