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Accurate confidence intervals for risk difference in meta-analysis with rare events

BACKGROUND: Meta-analysis provides a useful statistical tool to effectively estimate treatment effect from multiple studies. When the outcome is binary and it is rare (e.g., safety data in clinical trials), the traditionally used methods may have unsatisfactory performance. METHODS: We propose using...

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Bibliografiske detaljer
Udgivet i:BMC Med Res Methodol
Main Authors: Jiang, Tao, Cao, Baixin, Shan, Guogen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191692/
https://ncbi.nlm.nih.gov/pubmed/32349702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-00954-8
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