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The renin-angiotensin system: going beyond the classical paradigms

Thirty years ago, a novel axis of the renin-angiotensin system (RAS) was unveiled by the discovery of angiotensin-(1−7) [ANG-(1−7)] generation in vivo. Later, angiotensin-converting enzyme 2 (ACE2) was shown to be the main mediator of this reaction, and Mas was found to be the receptor for the hepta...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Santos, Robson Augusto Souza, Oudit, Gavin Y., Verano-Braga, Thiago, Canta, Giovanni, Steckelings, Ulrike Muscha, Bader, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191626/
https://ncbi.nlm.nih.gov/pubmed/30707614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00723.2018
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