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Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress

The free fatty acid receptor 3 (FFA3) is a nutrient sensor of gut microbiota-generated nutrients, the short-chain fatty acids. Previously, we have shown that FFA3 is expressed in β-cells and inhibits islet insulin secretion ex vivo. Here, we determined the physiological relevance of the above observ...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Regul Integr Comp Physiol
Hoofdauteurs: Priyadarshini, Medha, Cole, Connor, Oroskar, Gautham, Ludvik, Anton E., Wicksteed, Barton, He, Congcong, Layden, Brian T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191418/
https://ncbi.nlm.nih.gov/pubmed/32073900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00128.2019
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