Reduced expression of enolase-1 correlates with high intracellular glucose levels and increased senescence in cisplatin-resistant ovarian cancer cells

Despite good responses to first-line treatment with platinum-based combination chemotherapy, most ovarian cancer patients will relapse and eventually develop a platinum-resistant disease with a poor overall prognosis. The molecular events leading to the cisplatin resistance of ovarian cancer cells a...

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Vydáno v:Am J Transl Res
Hlavní autoři: Santana-Rivera, Yasmarie, Rabelo-Fernández, Robert J, Quiñones-Díaz, Blanca I, Grafals-Ruíz, Nilmary, Santiago-Sánchez, Ginette, Lozada-Delgado, Eunice L, Echevarría-Vargas, Ileabett M, Apiz, Juan, Soto, Daniel, Rosado, Andrea, Meléndez, Loyda, Valiyeva, Fatima, Vivas-Mejía, Pablo E
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191177/
https://ncbi.nlm.nih.gov/pubmed/32355541
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