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USP18 deubiquitinates and stabilizes Twist1 to promote epithelial-mesenchymal transition in glioblastoma cells

Aberrant activation of epithelial-mesenchymal transition (EMT) pathway drives the invasion and migration of multiple cancers including glioblastoma (GBM). Clinical interventions focused on inhibiting EMT are of increasing interest in the treatment of GBM. In the present study, we discovered that gli...

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Bibliografische gegevens
Gepubliceerd in:Am J Cancer Res
Hoofdauteurs: Cai, Xiaomin, Feng, Shuang, Zhang, Jiale, Qiu, Wenjin, Qian, Mengshu, Wang, Yuhai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: e-Century Publishing Corporation 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191102/
https://ncbi.nlm.nih.gov/pubmed/32368392
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