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TLR4 Cross-Talk With NLRP3 Inflammasome and Complement Signaling Pathways in Alzheimer's Disease

Amyloid plaques, mainly composed of abnormally aggregated amyloid β-protein (Aβ) in the brain parenchyma, and neurofibrillary tangles (NFTs), consisting of hyperphosphorylated tau protein aggregates in neurons, are two pathological hallmarks of Alzheimer's disease (AD). Aβ fibrils and tau aggre...

詳細記述

保存先:
書誌詳細
出版年:Front Immunol
主要な著者: Yang, Junling, Wise, Leslie, Fukuchi, Ken-ichiro
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190872/
https://ncbi.nlm.nih.gov/pubmed/32391019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00724
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