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An artificial chromosome ylAC enables efficient assembly of multiple genes in Yarrowia lipolytica for biomanufacturing

The efficient use of the yeast Yarrowia lipolytica as a cell factory is hampered by the lack of powerful genetic engineering tools dedicated for the assembly of large DNA fragments and the robust expression of multiple genes. Here we describe the design and construction of artificial chromosomes (yl...

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Dettagli Bibliografici
Pubblicato in:Commun Biol
Autori principali: Guo, Zhong-peng, Borsenberger, Vinciane, Croux, Christian, Duquesne, Sophie, Truan, Gilles, Marty, Alain, Bordes, Florence
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190667/
https://ncbi.nlm.nih.gov/pubmed/32350406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0936-y
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