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An artificial chromosome ylAC enables efficient assembly of multiple genes in Yarrowia lipolytica for biomanufacturing

The efficient use of the yeast Yarrowia lipolytica as a cell factory is hampered by the lack of powerful genetic engineering tools dedicated for the assembly of large DNA fragments and the robust expression of multiple genes. Here we describe the design and construction of artificial chromosomes (yl...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Guo, Zhong-peng, Borsenberger, Vinciane, Croux, Christian, Duquesne, Sophie, Truan, Gilles, Marty, Alain, Bordes, Florence
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190667/
https://ncbi.nlm.nih.gov/pubmed/32350406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0936-y
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