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ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity

Adenosine deaminases acting on RNA (ADARs) convert adenosine to inosine in double-stranded RNA. A-to-I editing of RNA is a widespread posttranscriptional process that has recently emerged as an important mechanism in cancer biology. A-to-I editing levels are high in several human cancers, including...

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Vydáno v:Oncogene
Hlavní autoři: Ramírez-Moya, Julia, Baker, Allison R., Slack, Frank J., Santisteban, Pilar
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190574/
https://ncbi.nlm.nih.gov/pubmed/32157211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1248-x
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