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Lineage hierarchies and stochasticity ensure the long-term maintenance of adult neural stem cells

The cellular basis and extent of neural stem cell (NSC) self-renewal in adult vertebrates, and their heterogeneity, remain controversial. To explore the functional behavior and dynamics of individual NSCs, we combined genetic lineage tracing, quantitative clonal analysis, intravital imaging, and glo...

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Publicat a:Sci Adv
Autors principals: Than-Trong, Emmanuel, Kiani, Bahareh, Dray, Nicolas, Ortica, Sara, Simons, Benjamin, Rulands, Steffen, Alunni, Alessandro, Bally-Cuif, Laure
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190328/
https://ncbi.nlm.nih.gov/pubmed/32426477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz5424
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