Activity of fibroblast-like synoviocytes in rheumatoid arthritis was impaired by dickkopf-1 targeting siRNA

BACKGROUND: Fibroblast-like synoviocytes (FLSs), resident mesenchymal cells of synovial joints, play an important role in the pathogenesis of rheumatoid arthritis (RA). Dickkopf-1 (DKK-1) has been proposed to be a master regulator of bone remodeling in inflammatory arthritis. Here, potential impaira...

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Detalhes bibliográficos
Publicado no:Chin Med J (Engl)
Main Authors: Liu, Yan-Ying, Wang, Shi-Yao, Li, Ying-Ni, Bian, Wen-Jie, Zhang, Lin-Qi, Li, Yu-Hui, Long, Li, Liu, Xia, Zhang, Xue-Wu, Li, Zhan-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2020
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190238/
https://ncbi.nlm.nih.gov/pubmed/32068606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CM9.0000000000000697
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