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Asymmetric Synthesis of Homocitric Acid Lactone
A short, diastereoselective synthesis of homocitric acid lactone is described. The key step is a bioinspired aldol addition to set the stereogenic center in an intermediate that requires only modest oxidation state manipulation to complete the synthesis. This approach enables rapid generation of iso...
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| Udgivet i: | J Org Chem |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7190193/ https://ncbi.nlm.nih.gov/pubmed/27685496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b01997 |
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