IL-27 signaling deficiency develops Th17-enhanced Th2-dominant inflammation in murine allergic conjunctivitis model

BACKGROUND: While most studies focus on pro-allergic cytokines, the protective role of immunosuppressive cytokines in allergic inflammation is not well elucidated. This study was to explore a novel anti-inflammatory role and cellular/molecular mechanism of IL-27 in allergic inflammation. METHODS: A...

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Pubblicato in:Allergy
Autori principali: Chen, Xin, Deng, Ruzhi, Chi, Wei, Hua, Xia, Lu, Fan, Bian, Fang, Gao, Ning, Li, Zhijie, Pflugfelder, Stephen C., de Paiva, Cintia S., Li, De-Quan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190079/
https://ncbi.nlm.nih.gov/pubmed/30515838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.13691
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