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IL10 deficiency promotes alveolar enlargement and lymphoid dysmorphogenesis in the aged murine lung

The connection between aging‐related immune dysfunction and the lung manifestations of aging is poorly understood. A detailed characterization of the aging IL10‐deficient murine lung, a model of accelerated aging and frailty, reconciles features of both immunosenescence and lung aging in a coherent...

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Publicado en:Aging Cell
Autores principales: Malinina, Alla, Dikeman, Dustin, Westbrook, Reyhan, Moats, Michelle, Gidner, Sarah, Poonyagariyagorn, Hataya, Walston, Jeremy, Neptune, Enid R.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189990/
https://ncbi.nlm.nih.gov/pubmed/32170906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13130
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