Primary Non-Response to Tumor Necrosis Factor Antagonists is Associated with Inferior Response to Second-line Biologics in Patients with Inflammatory Bowel Diseases: A Systematic Review and Meta-analysis

BACKGROUND AND AIMS: We sought to analyze whether response to a second-line biologic varies depending on the reason for discontinuation of the primary anti-TNF agent (primary non-response [PNR], secondary loss of response [LOR] after initial response, or intolerance), through a systematic review and...

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Bibliografiske detaljer
Udgivet i:J Crohns Colitis
Main Authors: Singh, Siddharth, George, John, Boland, Brigid S, Vande Casteele, Niels, Sandborn, William J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189966/
https://ncbi.nlm.nih.gov/pubmed/29370397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ecco-jcc/jjy004
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