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Synthesis and Reactivity of α-Haloglycine Esters: Hyperconjugation in Action

A general and efficient synthesis of α-haloglycine esters from commercially available feedstock chemicals, in a single step, is reported. The reactivity of these α-haloglycine esters with various nucleophiles was studied as surrogates of α-iminoesters upon activation with hydrogen-bond donor catalys...

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Publicat a:European J Org Chem
Autors principals: Samanta, Shyam S., Roche, Stéphane P.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189931/
https://ncbi.nlm.nih.gov/pubmed/32351314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201901033
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