TDP-43 is associated with a reduced likelihood of rendering a clinical diagnosis of dementia with Lewy bodies in autopsy-confirmed cases of transitional/diffuse Lewy body disease

BACKGROUND: Trans-active response DNA-binding protein of 43kDa (TDP-43) can be detected in up to 63% of autopsy confirmed Lewy body disease (LBD) cases. It is unclear whether TDP-43 is associated with a decreased likelihood of a clinical diagnosis of probable dementia with Lewy bodies (pDLB) during...

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Gepubliceerd in:J Neurol
Hoofdauteurs: Buciuc, Marina, Whitwell, Jennifer L., Boeve, Bradley F, Ferman, Tanis J., Graff-Radford, Jonathan, Savica, Rodolfo, Kantarci, Kejal, Fields, Julie A., Knopman, David S., Petersen, Ronald C., Parisi, Joseph E., Murray, Melissa E., Dickson, Dennis W., Josephs, Keith A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189897/
https://ncbi.nlm.nih.gov/pubmed/32006160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00415-020-09718-2
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