Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

BACKGROUND: Large numbers of autosomal sites are found differentially methylated in the aging genome. Due to analytical difficulties in dealing with sex differences in X-chromosome content and X-inactivation (XCI) in females, this has not been explored for the X chromosome. METHODS: Using data from...

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Gepubliceerd in:Genome Med
Hoofdauteurs: Li, Shuxia, Lund, Jesper B., Christensen, Kaare, Baumbach, Jan, Mengel-From, Jonas, Kruse, Torben, Li, Weilong, Mohammadnejad, Afsaneh, Pattie, Alison, Marioni, Riccardo E., Deary, Ian J., Tan, Qihua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2020
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189689/
https://ncbi.nlm.nih.gov/pubmed/32345361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-020-00736-3
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