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General Adaptation in Critical Illness: Glucocorticoid Receptor-alpha Master Regulator of Homeostatic Corrections

In critical illness, homeostatic corrections representing the culmination of hundreds of millions of years of evolution, are modulated by the activated glucocorticoid receptor alpha (GRα) and are associated with an enormous bioenergetic and metabolic cost. Appreciation of how homeostatic corrections...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Meduri, Gianfranco Umberto, Chrousos, George P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189617/
https://ncbi.nlm.nih.gov/pubmed/32390938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.00161
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