Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease

BACKGROUND: Mesenchymal stromal cell (MSC)-enriched products showed positive clinical outcomes in regenerative medicine, where tissue restoration and inflammation control are needed. GMP-expanded MSCs displayed an even higher potential due to exclusive secretion of therapeutic factors, both free and...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Ragni, Enrico, Perucca Orfei, Carlotta, De Luca, Paola, Mondadori, Carlotta, Viganò, Marco, Colombini, Alessandra, de Girolamo, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189600/
https://ncbi.nlm.nih.gov/pubmed/32345351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01677-9
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